What is AHCC®?

AHCC®has been used successfully to treat a wide range of health conditions, from minor ailments such as colds and flu, to serious diseases such as cancer, hepatitis, diabetes, and cardiovascular disease.

How can one dietary ingredient be effective against so many types of health problems? AHCC® is a functional food derived from healing mushrooms. Clinically tested and proven to support improved immune system health, AHCC® has anti-inflammatory, immune system enhancing, immunomodulatory, and antioxidant properties.
A strong and healthy immune system is critical in keeping you healthy and well. A strong immune system helps you fight infections such as colds and flus, and in protecting you against many serious and chronic diseases such as arthritis, heart disease, and autoimmune disease. As an extra bonus, AHCC® helps you better withstand the impacts of the treatments for many debilitating diseases and conditions.

Think of AHCC® as extra immune system support – ensuring you’re ready and able to withstand illness, disease, and inflammation. AHCC® is a focus of research at prestigious institutions through-out the world. AHCC® has been the subject of over 100 published papers, including 30 human clinical studies. Learn more about the pre-clinical and human clinical research into AHCC®

What is Authentic AHCC?

When shopping for AHCC®, ensure you purchase genuine AHCC®. Other products (mostly sold online) claiming to be AHCC® or “generic” versions of AHCC® using different longer names are misbranded and/or considered adulterated by the FDA. Click below for a full list of authentic AHCC® brands available for sale.

The AHCC® Facts?

Here are the facts on AHCC® that you need to know:

AHCC® is a standardized extract of cultured Lentinula edodes
AHCC® was developed in 1987.
AHCC® is shown to modulate the immune system by maintaining optimal natural killer (NK) cell activity, enhancing cytokine production, promoting T-cell and macrophage activity, and increasing the number and activity of dendritic cells.
AHCC® is a functional food that is rich in alpha-glucans.
AHCC® is used in hospitals, universities, and other institutions around the world.
For healthy people, AHCC® is useful in health maintenance and in preventing infection by aiding in the normal function of your immune system.
AHCC® is manufactured in Japan by Amino Up Co., Ltd.
AHCC® modulates your body’s innate immunity and supports healthy immune function.
In integrative oncology, research indicates that AHCC® may lead to longer post-operative survival, help support patients through chemotherapy, reduce the negative effects of chemotherapy and radiotherapy, and lead to an improvement in quality of life.

More Science Behind


In one gram of AHCC® there is an abundance of saccharides.


Some varieties of polysaccharides are known to have immunomodulatory effects.


AHCC® is unique because unlike other mushroom-sourced ingredients, AHCC® includes both the polysaccharides beta-glucans and alpha-glucans.


The saccharides found in AHCC® are polysaccharides, including oligosaccharides, starches, and other combinations of sugar molecules.

To learn more about AHCC® is derived, read the Patient’s Guide to AHCC® and watch our video on AHCC® Production Process Overview.

AHCC® is a focus of research at prestigious institutions through-out the world. AHCC® has been the subject of over 100 published papers, including 30 human clinical studies. Learn more about the pre-clinical and human clinical research into AHCC®.

How Does AHCC® Work??

Here is how AHCC® works to support your immune system:

Because AHCC® is a biological response modifier, it is able to turn up the dial on your natural immune response.
This allows you fight all kinds of threats to your health.
As you browse our website, you’ll learn how AHCC® has been successfully used to treat a wide range of health conditions such as colds and flus to serious diseases including cancer, hepatitis, diabetes, and cardiovascular disease.

You have 2 basic types of immunity: innate and adaptive.
Your innate immunity is made of four key players: cytokines, natural killer (NK) cells, macrophages, and dendritic cells.
Your adaptive immunity takes longer to react, but produces a specific response tailored to the particular microbe.
Your adaptive immunity is made of up of B and T cells.
Your innate immunity launches an immediate, non-specific attack against a threat.

Research shows us that AHCC® can modify your innate and adaptive immune system response.

This means you’re better able to withstand the impacts of a virus, bacteria, auto-immune attack, inflammatory response, or other disease such as cancer, hepatitis, or diabetes.

Learn more about how your immune system works and the key players in your innate and adaptive immunity.

We also have a video that explains how AHCC® works. Hear from Dr. Lawrence Kempf on how this unique and natural compound derived from Japanese medicinal mushrooms activates the immune system.

What Research is there about AHCC®?

AHCC® is used by over 1,000 healthcare facilities worldwide to:

AHCC® is the world’s most researched specialty immune system supplement

AHCC® is supported by over 30 human studies and more than 100 pre-clinical in vivo and in vitro studies.

Reduce the incidence of infections in both healthy and immune-compromised patients.
Help control HPV infections.
Improve patient outcomes.
Mange viral loads in Hepatitis-C patients.
Decrease chemotherapy side effects.
Help people with liver disease.

Please beware of some products sold online claiming to be “generic versions” of AHCC®. These are considered “adulterated” by the FDA. Click here to see all the authentic verified AHCC® products from various nutritional supplement brands.